The future of NSCLC treatment

Benjamin Besse, MD, PhD, Gustave Roussy Cancer Institute, Paris, describes new treatments and targets currently under investigation. Prof. Besse discusses the toxicity and progression-free survival (PFS) rate of sotorasib in first-line treatment as well as DZD9008 (sunvozertinib), an EGFR inhibitor assessed in patients with advanced non-small-cell lung cancer (NSCLC). Additional treatments discussed include patritumab deruxtecan, a novel HER3-directed antibody-drug conjugate (ADC), which has shown promise in patients with EGFR-mutated NSCLC. This interview took place at the American Society of Clinical Oncology (ASCO) 2021 Virtual Meeting.