Top 25 Pearls of Pulmonary Pathology Series. Max and Kevin discuss how to approach the diagnosis of malignant mesothelioma including immunohistochemical stains. Topic 5 Pear 1: The diagnosis of malignant mesothelioma should be easy. Visit www.6patterns.org for more. Twitter and Instagram @6Patterns. Videos are for education and entertainment only and should not be used as medical advice.