Small cell lung cancer: diagnosis and management
Small cell lung cancer, which occurs almost exclusively in smokers, is a malignancy characterised by rapid doubling time, high growth fraction and widespread metastasis at presentation. In this presentation, we will briefly discuss the classification of pulmonary Neuro-endocrine tumours by the World Health Organisation followed by a detailed discussion of the clinical features, lab evaluation and management of SCLC, both limited and extended stage. The frontline therapy in small cell lung cancer is etoposide and cisplatin along with thoracic radiotherapy and prophylactic cranial irradiation in patients who have a good response to therapy. Hyperfractionation of radiotherapy may provide some benefit but is also associated with increase incidence of complications. Newer agents for SCLC include Vandetanib and immunotherapy molecules, such as Iplimumab and nivolumab. Check out our other videos Ascites • Ascites: causes, diagnosis and management Aplastic anemia • Aplastic anemia: causes, diagnosis and man... Acute kidney injury • Acute kidney injury: mechanism, diagnosis ... Cardio renal syndrome • Cardiorenal Syndrome: Causes, diagnosis an... Vasculitis: Causes, clinical features and management • Vasculitis: Pathogenesis, types and treatment Dengue fever: clinical features and management • Dengue Fever: Clinical features and Manage... Addison’s disease • Addison's disease: causes, diagnosis and t... Hepatopulmonary syndrome • Hepatopulmonary Syndrome: Diagnosis and tr... Osteoporosis • Osteoporosis: Causes and treatment Hypertensive emergencies • Hypertensive emergencies Hepatorenal syndrome • Hepatorenal Syndrome Approach to a case of Anemia • Approach to Anaemia Meningitis and Encephalitis • Meningitis and Encephalitis: Causes and Tr... We would like to thank the following resources: Royalty free stock images from www.pexels.com Professional powerpoint templates by Creative Venus Youtube channel Initial smoke stock royalty free footage from www.videezy.com
