Learning objectives: 1. To recognise the central role of bone and CT scans for directing patient care despite their limitations 2. To showcase the MET-RADS standard for multiparametric WB-MRI for the baseline and follow-up examinations of patients with metastatic prostate cancers 3. To recognise potential uses of WB-MRI in different APC states in the context of other available next-generation imaging (NGI) 4. To acknowledge that higher-quality evidence on management & outcome impacts is needed if there is to be clinical acceptance & payments for NGI services Key references -Trabulsi EJ, et al. Optimum Imaging Strategies for Advanced Prostate Cancer: ASCO Guideline. J Clin Oncol. 2020; 38(17):1963-1996. -Perez-Lopez R, et al. Imaging Diagnosis and Follow-up of Advanced Prostate Cancer: Clinical Perspectives and State of the Art. Radiology. 2019; 292(2):273-286. -Padhani AR, et al. METastasis Reporting and Data System for Prostate Cancer: Practical Guidelines for Acquisition, Interpretation, and Reporting of Whole-body MRI Evaluations of Multiorgan Involvement in Advanced Prostate Cancer (MET-RADS-P). Eur Urol. 2017 Jan;71(1):81-92.