LeSean McCoy Runs in 2 First-Half TDs! | 49ers vs. Bills | NFL

RB LeSean (Shady) McCoy has a monster first half with 106 yards on 11 carries and 2 TD's. The San Francisco 49ers take on the Buffalo Bills during Week 6 of the 2016 NFL season. Subscribe to NFL: http://j.mp/1L0bVBu Start your free trial of NFL Game Pass: https://www.nfl.com/gamepass?campaign... Sign up for Fantasy Football! http://www.nfl.com/fantasyfootball The NFL YouTube channel is your home for immediate in-game highlights from your favorite teams and players, full NFL games, behind the scenes access and more! Check out our other channels: NFL Network    / nflnetwork   NFL Films    / nflfilms   For all things NFL, visit the league's official website at http://www.nfl.com/ Watch NFL Now: https://www.nfl.com/now Listen to NFL podcasts: http://www.nfl.com/podcasts Watch the NFL network: http://nflnonline.nfl.com/ Download the NFL mobile app: https://www.nfl.com/apps 2016 NFL Schedule: http://www.nfl.com/schedules Buy tickets to watch your favorite team: http://www.nfl.com/tickets Shop NFL: http://www.nflshop.com/source/bm-nflc... Like us on Facebook:   / nfl   Follow us on Twitter:   / nfl   Follow us on Instagram:   / nfl