Global climate change trends indicate that even with mitigation efforts, our planet will continue warming into the next century, leading to more extreme climate conditions and weather events. The Latin America and Caribbean region is particularly vulnerable to some of the most challenging aspects of climate change—sea-level rise affecting coastal cities, changes in precipitation impacting agriculture, glacial melting threatening water reserves. Population trends—like migration and urbanization—can exacerbate these challenges or, in some cases, serve as methods of adaptation. Building resilience to climate change through adaptation efforts and women's empowerment are key strategies for enabling continued development across the region in climate-uncertain times.