Topological Constraints of DNA Molecules

This video explores the topological constraints of DNA, focusing on the linking number, twist number, and writhing number. It explains how these parameters describe DNA’s conformation and supercoiling, the role of topoisomerases in managing these constraints, and how they affect DNA replication and transcription. The video illustrates these concepts with examples, including the differences between circular and linear DNA, and the energetic implications of supercoiling. View this video (and more like it) on LabXchange: https://www.labxchange.org/library/it...