Blood Production & Circulation Problems in Children | Unit 10 – Wong’s Pediatric Nursing (11th)

This unit presents a comprehensive examination of pediatric nursing care related to the circulatory, hematologic, immunologic, and cellular systems, focusing on the complex management of dysfunction in blood production and circulation. It begins with an in-depth analysis of cardiovascular dysfunction, categorized by hemodynamic characteristics rather than cyanosis alone. The content details congenital heart defects involving increased pulmonary blood flow, such as atrial and ventricular septal defects and patent ductus arteriosus, as well as obstructive defects like coarctation of the aorta. It further explores defects with decreased pulmonary blood flow, including tetralogy of Fallot, and mixed defects such as transposition of the great arteries and hypoplastic left heart syndrome. Essential nursing strategies for managing heart failure are outlined, emphasizing the use of digoxin, ACE inhibitors, and diuretics to improve cardiac function and fluid balance. The unit also covers acquired cardiovascular disorders, including infective endocarditis, acute rheumatic fever, and Kawasaki disease, alongside critical care for shock and anaphylaxis. Shifting to hematologic and immunologic function, the text evaluates red blood cell disorders, ranging from nutritional iron-deficiency anemia to genetic hemoglobinopathies like sickle cell anemia and beta-thalassemia. It describes the pathophysiology of sickle cell crises and the management of aplastic anemia and pancytopenia. Defects in hemostasis are examined, including hemophilia, immune thrombocytopenia, and disseminated intravascular coagulation, with a focus on blood transfusion therapy and safety. Immunologic deficiencies such as HIV and AIDS, severe combined immunodeficiency disease, and Wiskott-Aldrich syndrome are discussed in the context of preventing infection and managing antiretroviral therapy. Finally, the unit addresses pediatric oncology, detailing the epidemiology, diagnostic evaluation, and multimodal treatment of childhood cancers through surgery, chemotherapy, radiation, and hematopoietic stem cell transplantation. Specific malignancies covered include leukemias, lymphomas, brain tumors, neuroblastoma, bone tumors like osteosarcoma and Ewing sarcoma, Wilms tumor, rhabdomyosarcoma, and retinoblastoma. The summary concludes with a review of oncologic emergencies, such as tumor lysis syndrome, and the importance of long-term survivorship care. 📘 Read full blog summaries for every chapter: https://lastminutelecture.com 📘 Have a book recommendation? Submit your suggestion here: https://forms.gle/y7vQQ6WHoNgKeJmh8 Thank you for being a part of our little Last Minute Lecture family! ⚠️ Disclaimer: These summaries are created for educational and entertainment purposes only. They provide transformative commentary and paraphrased overviews to help students understand key ideas from the referenced textbooks. Last Minute Lecture is not affiliated with, sponsored by, or endorsed by any textbook publisher or author. All textbook titles, names, and cover images—when shown—are used under nominative fair use solely for identification of the work being discussed. Some portions of the writing and narration are generated with AI-assisted tools to enhance accessibility and consistency. While every effort has been made to ensure accuracy, these materials are intended to supplement—not replace—official course readings, lectures, or professional study resources. Always refer to the original textbook and instructor guidance for complete and authoritative information.