Frequent and Recurrent Cystitis and N-Acetylcysteine (NAC) in Urology

The topic of recurrent cystitis is always very current. 'Occhio Clinico e non solo' returned to the topic with Debora Marchiori (Urologist, Bologna). For more information, visit http://www.deboramarchiori.it/ "Many patients ask me what the magic recipe is for defeating these 'cursed' recurring cystitis. Many women come to see me or contact me to see if there's a cure for a disease that seems nonexistent in public opinion, yet afflicts them, destroys them psychologically, and even leads them to give up their moments of love. In reality, there are recipes to try to reduce or eliminate a problem that in most cases arises from a weakening of the mucous membranes. What is certain is that there are bacteria inside 'containers' like the bladder. Even if we repair the fragile mucous membranes, we still need to eliminate these enemies that colonize our urinary tract. The conflict arises from the fact that the patient doesn't want to take the antibiotic therapy she's been taking for years, which has been frustrating, given that At the end of the treatment, the same symptoms recurred. In reality, there is an ingredient that enhances the antibiotic's effect and, above all, eliminates these enemies. Specifically, it is NAC, or N-Acetylcysteine. This molecule is generally used for respiratory problems as it thins mucus plugs. In fact, we have seen that it is also very effective for urinary tract infections, especially those caused by Escherichia coli. This is a particular bacterium that nests in our urinary tract and protects itself within mucus plugs. These mucus plugs are practically impermeable to all types of antibiotics, even the most powerful ones. This is why in many cases antibiotic therapy, even if appropriate according to the susceptibility test, seems to fail. It is because the bacteria remain protected within the bladder and therefore—as soon as the antibiotic's effect wears off—they reinfect the urinary tract. Using a product that dissolves mucus plugs means exposing the bacteria by depriving them of their 'fortifications' and thus the antibiotic, combined if possible with D-Mannose has a more powerful, more bactericidal effect than antibiotic therapy alone, which would only kill a small portion of the pathogens. Therefore, let's remember that in the case of urinary tract infections, the inclusion of this molecule, N-Acetylcysteine, in therapy can really make a difference. Obviously, the patient cannot be cured using this ingredient alone; we must contextualize the origin of these pathologies and focus on comprehensively eliminating all the pathogenic noxae that create this disorder, which impacts the patients' quality of life.