Dr Giuseppe Barone, The Royal Marsden Hospital Paediatric Drug Development Dr Barone, Royal Marsden Hospital, describes why new drugs are needed for children with neuroblastoma. The presentation describes the use of targeted agents in cancer treatment and which targets are useful to explore in neuroblastoma, focusing on the ALK gene. He discusses the current and future work into ALK targeted therapies and how to improve the treatment strategy for children with cancer.