Academy of Science of South Africa (ASSAf), The Royal Society A transdisciplinary project of science academies explores perspectives from Africa, Asia, the Americas and Europe for mitigation and adaptation. Discussion will explore how scientific evidence can be better used to inform policy making for health, integrated at local, regional, and global levels. Speakers: Introduced by ASSAf and RS with Volker ter Meulen and Andy Haines (project co-chairs) and speakers/discussants from regional working groups in Africa, Asia, Americas, and Europe (expected to be combined virtual and physical event)