Lysogenic cycle in virology ✨ Check description for details #microfunwithteju #virus #bacteriophage

Lysogenic Cycle in Virology Introduction : One of two phage replication strategies (other = lytic). Temperate phages (e.g., λ phage of E. coli). Phage DNA integrates into host → stays dormant → later may switch to lytic. Key Terms : Temperate phage → can do both lytic & lysogenic. Prophage → phage DNA integrated in bacterial chromosome. Lysogeny → bacterium carrying prophage. Induction → prophage excised → enters lytic (triggered by UV, stress, chemicals). Stages (i) Adsorption & Penetration → phage attaches + injects DNA. (ii) Decision point → cI repressor = lysogeny Cro protein = lysis (iii) Integration → genome joins host DNA (via integrase at attP–attB). (iv) Maintenance → prophage replicates with host; repressor keeps it dormant. (v) Induction → stress → SOS response → RecA inactivates repressor → prophage excised → lytic cycle starts. Biological Significance : Survival strategy : virus hides till conditions are right. Phage conversion : prophage genes give new traits (e.g., diphtheria toxin, cholera toxin, botulinum toxin). Horizontal gene transfer : spreads virulence & antibiotic resistance genes. Lytic vs Lysogenic : Phage type → Virulent vs Temperate. Outcome → Host lysed vs Host survives. Genome → Separate vs Integrated. Gene expression → Immediate vs Repressed. Duration → Short vs Long. Examples → T4 vs λ, P22, Mu. Applied Aspects : Medical → explains toxin production in pathogens. Molecular Biology → λ phage integration = cloning tool. Phage therapy → need to understand lysogeny for safety. #microfunwithteju #microbiology #Virology #Bacteriophage #LysogenicCycle #LyticCycle #PhageBiology #MolecularBiology #CellBiology #viralshort #trendingshorts #trendingreels #trendingvideo #EduContent #BiologyNotes #neet #csirnet #viral #algorithm #views #followforfollowback #trend #trendingreel #disease #DidYouKnowScience #KnowledgeIsPower #InstaScience #ExploreScience #FutureScientists #learnonyoutube