ER Retrieval Pathway | Cell Bio | Video Textbooks - Preview

Watch the full video at https://www.jove.com/v/11956?utm_sour... Explore our full cell biology video textbook at https://www.jove.com/science-educatio... JoVE is the world-leading producer and provider of science videos with a mission to accelerate scientific research and education. Millions of scientists, educators and students across 1500+ High Schools, colleges and universities worldwide use JoVE’s library of 17,000+ videos for teaching, learning and research. JoVE High Schools offers expert-created video textbooks, lab videos, science experiment videos, interactive assessments, and seamless integration into school systems. These comprehensive learning resources help educators tackle teaching challenges, engage students, and meet curriculum requirements, enhancing the high school learning experience. Subscribe to our YouTube Channel -    / @jovehighschools   Follow us on - Facebook -   / jovehighschools   Instagram -   / jovehighschools   In the secretory pathway, proteins are transported from one organelle to another in vesicles that bud off from membranes. To prevent a misfolded protein or a resident protein of an organelle from being relocated, the ER retrieval pathway returns escaped proteins back to the ER. Generally, resident proteins are retained in the ER by chaperones such as BiP , while other proteins are recruited as cargo.