DevoWorm (2025, #30): Mathematical Modeling of Cell Deformation, Biotensegrity and Superstability

Attendees: Bradly Alicea and Susan Crawford-Young Modeling the surface of an embryo and its deformation processes: invagination during gastrulation. The role of adhesion in cell migration and changes in shape. Skeletal mesh of a cell sheet and the dynamics of dynamic alignment. Superstability of tensegrity structures and the connection between human musculoskeletal geometry and the dynamics of cell sheets. What can be learn through the application of closed kinematic chains? Coupled oscillators, kinematic chains, and the generation of chaotic behavior. Stability as a homeostatic imperative. Dries et.al (2025). Studying Gastrulation by Invagination: the bending of a cell sheet by mechanical cell properties using 3D deformable cell based simulations. PLoS Computational Biology, 21(6), e1013151. Scarr et.al (2025). Biotensegrity is the Superstability Hypothesis for Biology. BioSystems, 105569.