This workshop focused on the treatment of patients during the Covid-19 pandemic and the lessons learned concerning therapeutic choices. The instructors discuss the determinants of therapeutic decision making while in a pandemic, as well as discuss the therapeutic approach in different clinical settings considering patient severity: mild, moderate-severe and critical. This virtual workshop took place at the ESCMID Conference on Coronavirus Disease (ECCVID) which initially took place online from Wednesday 23rd to Friday 25th September 2020 and covered many aspects of the COVID-19 pandemic. Other ESCMID Links: ECCMID: https://www.eccmid.org Twitter: / escmid Facebook: / escmid LinkedIn: / escmid