sickel cell anemia.

sickel cell anemia.

serious inherited blood disorder where red blood cells, normally round, smooth and flexible, become stiff, rigid, sticky, and sickle-shaped (like a crescent moon), leading to blockages in small blood vessels, severe pain crises, anemia, fatigue, and potential organ damage. Caused by a mutated gene, it's common in people of African, Asian, Mediterranean, and Indian descent, requiring lifelong management with treatments like pain relief, hydration, antibiotics, blood transfusions, and newer options like gene therapy, with a bone marrow transplant being the only potential treatment.