DISC1 knockdown leads to behavioral deficits

Watch and listen as Akira Sawa and colleagues take you on a personally guided tour of their findings that transient knockdown of DISC1, a genetic susceptibility factor for schizophrenia, in the pre- and peri-natal stages leads to abnormalities in postnatal mesocortical dopaminergic maturation and behavioral abnormalities after puberty. Read more in Niwa et al., Neuron 65(4). http://www.cell.com/neuron/abstract/S...