Grignard Reaction-Ester/Mechanism & Product (1° or 3° Alcohol)/Alkyl Halides|@chemistrywallah120
Grignard Reaction with Ester | Complete Mechanism Explained | Chemistry Wallah The Grignard Reaction with Esters is one of the most powerful transformations in Organic Chemistry, widely tested across MDCAT, NEET, JEE, ETEA, and international competitive exams. This lecture explains, in a clear and exam-oriented way, how Grignard reagents convert esters into tertiary alcohols, why two moles of RMgX are required, and how the ketone intermediate forms and reacts further. This video strengthens conceptual understanding and helps students solve MCQs, mechanism questions, and product-prediction problems with confidence. --- 🌟 What You Will Learn ✔ Nature and Reactivity of Grignard Reagents Polar carbon–magnesium bond Strong nucleophilic and basic character Structure, preparation, and behavior ✔ Why Esters Undergo Two Consecutive Attacks Electrophilic carbonyl carbon OR group acting as a leaving group Formation of a ketone intermediate Immediate second nucleophilic attack ✔ Complete Step-by-Step Mechanism 1. First nucleophilic attack by RMgX → tetrahedral intermediate 2. Collapse of intermediate → formation of ketone 3. Second attack by RMgX 4. Acidic hydrolysis → formation of tertiary alcohol ✔ Final Product Explanation Why esters always give tertiary alcohols Stability of intermediates Comparison with aldehydes and ketones (written without greater-than symbols) --- 🎯 Exam-Focused Outcomes By the end of this lecture, students will be able to: Predict products when esters react with Grignard reagents Understand intermediate structures Solve mechanism-based MCQs quickly Recognize reaction patterns in synthesis problems Apply concepts in board exams and competitive tests --- 🧪 Key MCQ Concepts Covered Reactivity order explained in words (aldehydes are more reactive than ketones, and ketones are more reactive than esters) Reason for two-step addition Importance of acidic hydrolysis Why tertiary alcohols are formed Grignard reagent as a strong nucleophile These points frequently appear in MDCAT, NEET, JEE, ETEA, NUMS, NUST and other major exams. --- 📘 Why This Lecture Matters This lecture enhances understanding of: Organic reaction mechanisms Synthetic pathways Carbonyl chemistry Formation of complex alcohols Essential for both medical and engineering exam aspirants. --- 🌍 About Chemistry Wallah We deliver high-quality, conceptual chemistry lectures for FSc, MDCAT, NEET, JEE, ETEA, and international students. Our focus is clarity, mechanism understanding, and real exam problem-solving. --- 💬 Final Words If you found this lecture helpful: 👍 Like 💬 Share your questions 🔔 Subscribe for more premium content 📤 Share with classmates Your support helps us continue producing valuable educational content for students worldwide.
