CDK4/6 inhibitor switching in HR+/HER2- metastatic breast cancer

CDK4/6 inhibitor switching in HR+/HER2- metastatic breast cancer

Paola Zagami, MD, European Institute of Oncology IRCSS (IEO), Milan, Italy, comments on the potential for switching CDK4/6 inhibitors in HR+/HER2- metastatic breast cancer, highlighting the importance of this approach in minimizing treatment interruptions due to adverse events. The FDA indication allows for long-term use of first-line treatment without frequent switches, and this approach is currently crucial for oncologists, as it can improve patient outcomes and quality of life. This interview took place during the 2025 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL. These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.