This official launch, held online on 2 December 2021, marked the publication of the report of the EASL–Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality. 0:00 Opening remarks 2:26 Richard Horton, Editor-in-Chief, The Lancet 9:26 Ursula von der Leyen, Keynote statement on EU health policy 15:56 Michael Manns, Overview of the EASL-Lancet Liver Commission 25:00 Nick Sheron, The burden of liver disease in Europe 32:50 Shira Zelber-Sagi, Children and the power of digital marketing 39:44 Patrizia Carrieri, Stigma as a barrier in pathways of liver care 46:20 Rachel Pryke, Primary care hepatology 53:53 Pere Ginès, A paradigm shift in hepatology 1:00:27 Panel discussion "How to move from recommendations to action?" 1:27:12 Q&A session 1:39:22 Sabine Kleinert, Future opportunities of a Lancet Commission 1:44:57 Tom Hemming Karlsen, Closing remarks This prestigious event marks the culmination of many years of collaboration, together with a new momentum toward its solid implementation. The discussion engaged commissioners (contributors to the report), other high-level actors and experts from the European institutions, and patient representatives. Key topics of the report were discussed, as well as how the European Union policy and funding initiatives can support both the recommendations and application of good practices throughout the EU. Speakers included: Ursula von der Leyen, President of the European Commission: with keynote presentation at • EASL-Lancet Liver Commission keynote by Ur... Michael Manns, EASL–Lancet Commission Co-chair (Germany) Nick Sheron (United Kingdom) Shira Zelber-Sagi (Israel) Patrizia Carrieri (France) Rachel Pryke (United Kingdom) Pere Ginès (Spain) Shlomo Vinker, WONCA (Israel) Michele Cecchini, OECD (France) Rachel Halford, WHA (United Kingdom) Sabine Kleinert, The Lancet (United Kingdom) Tom Hemming Karlsen, EASL–Lancet Commission Co-chair (Norway) Find out more at: https://easl.eu/PR-easl-lancet