Ever wondered why embryos fail to implant? Would a euploid embryo overcome this problem? The December 2020 Fertility and Sterility by Pirtea et al. study the true prevalence of recurrent implantation failure. This Journal Club Global discusses the findings and clinical impact with the authors. View the Journal Club Webinar at https://www.asrm.org/resources/videos... Visit Fertility and Sterility at https://www.fertstert.org/