In November 1348, Amicia de Rune is a 15-year-old French girl of noble descent who lives in Aquitaine during the Hundred Years' War between England and France. Her 5-year-old brother, Hugo, has been ill since birth their mother, Beatrice, an alchemist, has sheltered him in their estate while trying to devise a cure. While hunting with her father Robert in the forest, Amicia encounters an unusual substance on the ground, and her dog Lion is gruesomely consumed by an unseen entity. French Inquisition troops, led by Lord Nicholas, arrive at the de Rune estate in search of Hugo, executing Robert and slaughtering the family servants. Beatrice helps her children escape and instructs Amicia to take Hugo to a doctor named Laurentius. The children flee to a nearby village, where they learn that hordes of rats have been spreading the black plague (known as the Bite). The two are wanted by the Inquisition and have to evade the villagers Amicia and Hugo eventually reach Laurentius's farm and find him severely ill with the plague. Laurentius implores Amicia to finish her mother's work seconds before the farm is overrun by rats the siblings flee with Laurentius's apprentice, Lucas, to seek the Chateau d'Ombrage, which once belonged to the de Rune family. As they cross a battlefield patrolled by English soldiers, Lucas explains that Hugo's blood carries a supernatural evil called the Prima Macula, which has lain dormant within certain noble bloodlines since the Plague of Justinian. Beatrice and Laurentius had been trying to find an elixir that would mitigate Hugo's symptoms, while Vitalis Benevent, the Grand Inquisitor of France, seeks to harness Hugo's power so that the Inquisition can rule France. Hugo and Amicia are briefly captured by the English, but escape with the help of sibling thieves Mélie and Arthur; Arthur is captured as the others escape to Chateau d'Ombrage. Do subscribe - like - share #ps5gameplay #aplaguetaleinnocence