Big Daddies can be very difficult opponents, but using this simple, obvious, and "too good to be true" technique makes short work of them every time. The trick is to use the drill... Get in his face and overwhelm him using the drill spin, and electro bolt works very well to freeze him, or winter blast can be used. Make sure you have at least a half tank of drill fuel beforehand. The "Freezing Drill" Gene Tonic is a nice added touch but not necessary. And it helps to have Gene Tonics like "Drill Power" and "Drill Lurker" as well. You should probably have 2 EVEs and First Aid Kits and be prepared to heal at least once or twice as he will still hurt you during your drilling assault, depending which difficulty setting you are playing on. As usual, this clip is on the hardest difficulty setting available, in this case called "Hard".