Fighting the big wolf twice will reward the player a decrease of the wolf's health by 15% for the boss fight. After difficulties of fighting the wolf along with the little wolves, I implement the Toxic Mist cheese strategy inside the tower to lower the big wolf's health. The toxic damage works well against this wolf. Also, the wolf is weak to fire. I have yet to beat this boss, and this one gives me more difficulties than the Sister Friede fight, surprisingly. The cheese strategy works for any characters with 15 faith. A level 1 character can use it as long as the Priestess Ring is used. This was done in NG+7.