Uric Acid: A KEY Cause of Weight Gain & INSULIN RESISTANCE (Lower It Today!) | Dr. David Perlmutter
Dr. David Perlmutter is a Board-Certified Neurologist and five-time New York Times bestselling author. He serves on the Board of Directors and is a Fellow of the American College of Nutrition. Today we’re discussing David's new book, Drop Acid. It focuses on the pivotal role of uric acid in metabolic diseases. Reducing high uric acid levels through dietary and lifestyle tweaks will help you lose weight, prevent (and reverse) disease, and live a long and healthy life. Subscribe to The Jesse Chappus Show on YouTube: / @jessechappus (And be sure to hit the 🔔 to get notified when new videos are released!) In this episode, we discuss: 00:00 - Intro 00:26 - The role of uric acid 03:22 - Fructose is directly metabolized into uric acid 09:06 - Fruit in moderation does not elevate uric acid 11:20 - Sources of fructose to avoid 15:16 - What is the optimal range for uric acid levels 22:24 - Estrogen helps with uric acid excretion after menopause 23:44 - Alternative sweetener recommendations + what to avoid 28:51 - Purines increase uric acid 34:37 - The correlation between salt consuption and obesity 42:37 - Lack of restorative sleep is associated with an elevation of uric acid 46:29 - Walking after dinner improves sleep 47:50 - Time-restricted eating is a powerful tool to improve metabolic health 50:12 - Uric acid levels rise during longer fasts + how long it takes to lower 1:02:29 - Luteolin is as effective as Allopurinol for lowering uric acid 1:03:31 - The powerful benefits of quercetin 1:04:51 - Counteracting roles of AMP kinase vs AMP deaminase 1:06:57 - Exercise activates AMP kinase 1:10:01 - When did the uricase mutation take place? 1:14:38 - The problem with sports drinks + healthy alternatives 1:16:32 - Check your blood sugar levels with a continuous glucose monitor 1:20:46 - Consuming coffee is associated with lower uric acid levels 1:23:15 - The dietary approach to lowering uric acid Show notes: https://jessechappus.com/457 Listen & subscribe to The Jesse Chappus Show ✩ Apple Podcasts: https://podcasts.apple.com/podcast/id... ✩ Spotify: https://open.spotify.com/show/5A1vpgP... Connect with The Jesse Chappus Show ✩ Website: https://jessechappus.com ✩ Instagram: / jessechappusshow #drdavidperlmutter #jessechappus #dropacid About the Podcast Jesse Chappus has in-depth conversations with health and wellness leaders from around the world. Topics include lifestyle, nutrition, fitness, self-help, sleep, meditation, spirituality and so much more. Tune in weekly to take your health to the next level! Disclaimer The opinions expressed in this video are those of the guest and are presented for informational purposes only. This content is not medical advice. Please consult your healthcare provider regarding any health-related decisions.
