RRP के लक्षण और इलाज 1 मिनट में जानें हिंदी

Treatment of Recurrent Respiratory Papillomatosis (RRP) By Dr. Prof. Vishal Pathania, ENT Specialist, Gurgaon What is Recurrent Respiratory Papillomatosis (RRP)? Recurrent Respiratory Papillomatosis is a rare but serious condition caused by the Human Papilloma Virus (HPV), mainly types 6 and 11. It leads to the growth of benign (non-cancerous) tumors called papillomas in the airway, especially in the voice box (larynx), windpipe (trachea), and sometimes even deeper into the lungs. Despite being benign, these growths can severely affect breathing and voice quality, and often recur after treatment—hence the name. Symptoms of RRP Hoarseness or weak voice Difficulty breathing, especially in children Chronic cough Stridor (noisy breathing) Frequent respiratory infections Airway obstruction in severe cases Diagnosis Diagnosis is typically made via: Laryngoscopy: A small camera inserted through the nose or mouth to visualize the vocal cords. Biopsy: To confirm the diagnosis and rule out malignancy. HPV Testing: Identifying the specific virus type may help guide treatment. Treatment Options for RRP 1. Surgical Removal (Mainstay Treatment) Microlaryngoscopy with Microdebrider or Laser: The most effective and commonly used method to remove papillomas. Lasers (like CO₂ or KTP) help in precision removal with minimal bleeding. Multiple surgeries may be needed due to recurrence. 2. Adjuvant Therapy (For Severe or Recurrent Cases) When surgery alone isn't enough, additional therapies are considered: Cidofovir Injections: An antiviral medication injected directly into lesions to slow regrowth. Bevacizumab (Avastin): An anti-angiogenic drug that can reduce blood supply to papillomas, sometimes injected or given systemically. Interferon Therapy: Boosts the immune system to control the virus, but used less now due to side effects. Photodynamic Therapy: Uses light-activated drugs to destroy papilloma cells—experimental but promising. 3. Vaccination The HPV vaccine (Gardasil 9) is not a treatment, but it has shown some benefit in reducing recurrence when given after diagnosis. It is highly recommended for prevention, especially in children and adolescents. Follow-Up and Monitoring Patients with RRP need regular monitoring due to the risk of recurrence and, in rare cases, progression to cancer. Follow-ups may include: Periodic endoscopy Voice assessments Chest imaging in extensive cases Prognosis Most cases can be managed with regular treatment, though repeated surgeries are often required. Juvenile-onset RRP (starting in childhood) tends to be more aggressive than adult-onset. With advances in therapy and early intervention, quality of life can be significantly improved. Conclusion Recurrent Respiratory Papillomatosis may be a challenging condition, but with timely diagnosis and a combination of surgical and medical therapies, patients can lead active, fulfilling lives. If you or your child are experiencing persistent hoarseness or breathing difficulty, consult an ENT specialist promptly. For expert care in managing RRP and other voice or airway disorders, book a consultation with Dr. Prof. Vishal Pathania at Pathania ENT Clinic, Gurgaon.