Radiotherapy clinical trials play a vital role in improving cancer treatment, patient outcomes, and quality of life. In this video, we explore what radiotherapy clinical trials are, why radiotherapy clinical trials are important, address some frequently asked questions from real patients, present a case study on a recent prostate radiotherapy clinical trial, and explain why you might be interested in taking part in a radiotherapy clinical trial. Clinical trials help develop more precise, personalised, and effective radiotherapy treatments, with the goal of achieving better tumour control while reducing side effects. For more information, please speak to your clinical oncologist or radiotherapy department.