Effects|Deficiency|1/4|Vitamin|D|Biochemistry|Pharmacy Technician|Dr Muhammad Naeem Asghar RPh @drnaeempharmacist381 Effect of Vitamin -D deficiency Deficiency of vitamin D may cause rickets in children and Osteomalacia in adults. Rickets It is a disease primarily due to a deficiency of dietary intake of vitamin D but an inadequate supply of calcium, phosphorus and sunlight may also play a part. The deficiency of vitamin D results in a lowered calcium level which stimulates the secretion of PTH which acts to restore the plasma calciumat the expense of bone calcium. Serum Phosphate level is decreased to 1 -2 mg% (Normal = 4-6mg %), due to parathyroid hormone activity. Rickets is also seen clinically when there is a defect in the conversion to calcitriol.