#MRCP PART ONE#PASSMEDICINE 2020 Basic Science 25

Keys of Basic Science UPPER LIMB ANATOMY RADIAL NERVE ULNAR NERVE LOWER LIMB ANATOMY POPLITEAL FOSSA RENAL ANATOMY FORAMINA OF THE SKULL CRANIAL NERVES SPINAL CORD BRACHIAL PLEXUS DERMATOMES COLLAGEN CELL ORGANELLES CELL CYCLE CELL DIVISION MICROTUBULES MEMBRANE RECEPTORS CELL SURFACE PROTEINS MUSCLE CONTRACTION TROPONIN SECOND MESSENGERS CARDIOVASCULAR PHYSIOLOGY CARDIAC ACTION POTENTIAL ATRIAL NATRIURETIC PEPTIDE NITRIC OXIDE ENDOTHELIN RESPIRATORY PHYSIOLOGY RESPIRATORY PHYSIOLOGY: CONTROL RESPIRATORY PHYSIOLOGY: LUNG COMPLIANCE RESPIRATORY PHYSIOLOGY: HYPOXIA PULMONARY SURFACTANT GASTROINTESTINAL HORMONES RENAL PHYSIOLOGY RENIN RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM ERYTHROPOIESIS GROWTH HORMONE ANTIDIURETIC HORMONE PROLACTIN ADRENAL MEDULLA CEREBRAL PERFUSION PRESSURE ALKALINE PHOSPHATASE ARACHIDONIC ACID METABOLISM IRON METABOLISM FOLATE METABOLISM CALCIUM METABOLISM VITAMIN B1 (THIAMINE) VITAMIN B2 (RIBOFLAVIN) VITAMIN B3 (NIACIN) VITAMIN B6 (PYRIDOXINE) VITAMIN C (ASCORBIC ACID) VITAMIN C DEFICIENCY (SCURVY) VITAMIN D RICKETS VITAMIN D-RESISTANT RICKETS VITAMIN K IMMUNE SYSTEM CELLS: INNATE IMMUNE RESPONSE IMMUNE SYSTEM CELLS: ADAPTIVE IMMUNE RESPONSE IMMUNOGLOBULINS T-HELPER CELLS CYTOKINES IL-1 INTERFERON LEUKOTRIENES ACUTE PHASE PROTEINS HYPERSENSITIVITY MOLECULAR BIOLOGY TECHNIQUES POLYMERASE CHAIN REACTION OBESITY: PHYSIOLOGY SLEEP STAGES PENETRANCE AND EXPRESSIVITY ANTIBIOTICS: MECHANISM OF ACTION ANTIBIOTICS: PROTEIN SYNTHESIS INHIBITORS ANAESTHETIC AGENTS LOCAL ANAESTHETIC AGENTS MUSCLE RELAXANTS POST OPERATIVE FLUID MANAGEMENT POTASSIUM SPARING DIURETICS FIBRATES EZETIMIBE BREASTFEEDING: CONTRAINDICATIONS MITOCHONDRIAL DISEASES COMPLEMENT DEFICIENCIES PARATHYROID GLANDS AND DISORDERS OF CALCIUM METABOLISM HUNGRY BONE SYNDROME DISORDERS OF SEX HORMONES TURNER’S SYNDROME METABOLIC ALKALOSIS HYPOCALCAEMIA: FEATURES HYPOCALCAEMIA: CAUSES AND MANAGEMENT HYPERCALCAEMIA: MANAGEMENT HYPONATRAEMIA HYPONATRAEMIA: TREATMENT 94 SIADH: CAUSES 95 HYPERNATRAEMIA HYPOKALAEMIA HYPOKALAEMIA AND HYPERTENSION PSEUDOHYPERKALAEMIA HYPERKALAEMIA HYPERURICAEMIA HYPOPHOSPHATAEMIA HLA ASSOCIATIONS AUTOSOMAL DOMINANT AUTOSOMAL DOMINANT CONDITIONS FAMILIAL HYPERCHOLESTEROLAEMIA ACHONDROPLASIA AUTOSOMAL RECESSIVE CONDITIONS CYSTIC FIBROSIS CYSTIC FIBROSIS: FEATURES CYSTIC FIBROSIS: MANAGEMENT GALACTOSAEMIA HOMOCYSTINURIA PHENYLKETONURIA ALKAPTONURIA ANDERSON-FABRY DISEASE X-LINKED DOMINANT X-LINKED RECESSIVE X-LINKED RECESSIVE CONDITIONS ALPHA-THALASSAEMIA DISSEMINATED INTRAVASCULAR COAGULATION CHILDHOOD SYNDROMES FRAGILE X SYNDROME NOONAN SYNDROME PRADER-WILLI SYNDROME WILLIAM’S SYNDROME DIGEORGE SYNDROME MCCUNE-ALBRIGHT SYNDROME DOWN’S SYNDROME: EPIDEMIOLOGY AND GENETICS DOWN’S SYNDROME: FEATURES HIRSCHSPRUNG’S DISEASE TRINUCLEOTIDE REPEAT DISORDERS INHERITED METABOLIC DISORDERS CONGENITAL HEART DISEASE: TYPES PATENT DUCTUS ARTERIOSUS TETRALOGY OF FALLOT TRANSPOSITION OF THE GREAT ARTERIES EBSTEIN’S ANOMALY ATHEROSCLEROSIS HYPERLIPIDAEMIA: SECONDARY CAUSES HYPERLIPIDAEMIA: MANAGEMENT DIABETIC NEPHROPATHY MUCORMYCOSIS URINARY CASTS RENAL TUBULAR ACIDOSIS RENAL STONES EXOTOXINS AND ENDOTOXINS STAPHYLOCOCCI ESCHERICHIA COLI CAMPYLOBACTER MYCOBACTERIUM MARINUM CONGENITAL INFECTIONS CHILDHOOD INFECTIONS DIARRHOEA IN CHILDREN CHICKENPOX MEASLES HAND, FOOT AND MOUTH DISEASE ENTEROVIRUSES SCARLET FEVER BRONCHIOLITIS CROUP HERPES SIMPLEX VIRUS HIV: IMMUNOLOGY HIV: THE VIRUS ACUTE EPIGLOTTITIS CHOLANGITIS POST-SPLENECTOMY SEPSIS MECKEL’S DIVERTICULUM APPENDICITIS IN CHILDREN PYLORIC STENOSIS RICKETTSIAE HELMINTHS WUCHERERIA BANCROFTI THREADWORMS CUTANEOUS LARVA MIGRANS KNEE PROBLEMS: CHILDREN AND YOUNG ADULTS KAWASAKI DISEASE ONCOGENES TUMOUR SUPPRESSOR GENES p53 WILMS’ TUMOUR CNS TUMOURS BRAIN TUMOURS ACUTE TUBULAR NECROSIS TEMPORAL ARTERY BIOPSY FITNESS TO FLY STATISTICAL TERMS: DESCRIPTIVE STATISTICS CONFIDENCE INTERVAL AND STANDARD ERROR OF THE MEAN VARIANCE NORMAL DISTRIBUTION SKEWED DISTRIBUTIONS PRE- AND POST- TEST ODDS AND PROBABILITY ODDS AND ODDS RATIO HAZARD RATIO RELATIVE RISK NUMBERS NEEDED TO TREAT AND ABSOLUTE RISK REDUCTION RELIABILITY AND VALIDITY BIAS FUNNEL PLOT CONFOUNDING CORRELATION AND LINEAR REGRESSION SCREENING TEST STATISTICS DATA TYPES CLINICAL TRIAL: PHASES STUDY DESIGN STUDY DESIGN: EVIDENCE AND RECOMMENDATIONS STUDY DESIGN: NEW DRUGS SIGNIFICANCE TESTS SIGNIFICANCE TESTS: TYPES INTENTION TO TREAT ANALYSIS SCREENING: WILSON AND JUNGER CRITERIA INCIDENCE AND PREVALENCE GMC GUIDANCE: CONFIDENTIALITY PATIENTS WHO REFUSE TREATMENT