Cramping after an embryo transfer is a normal symptom that can be caused by implantation, the effects of progesterone and fertility medications, or the stress of the procedure. While mild cramping can be a positive sign of successful implantation, it's important to contact your fertility specialist if you experience severe or persistent pain, heavy bleeding, or other concerning symptoms, as these could indicate a more serious issue. Common Causes of Cramping Implantation: As an embryo attaches to the uterine lining, it can cause mild cramping and discomfort, similar to menstrual cramps. Progesterone and Medications: The progesterone and other fertility medications you take after the transfer can cause hormonal changes, leading to symptoms like bloating, fatigue, and cramping. Stress and Physical Activity: The procedure itself can cause stress on the body, leading to uterine contractions and cramping. Avoiding strenuous activity and getting rest can be beneficial. Gas and Constipation: Hormonal changes can also contribute to digestive issues like gas and constipation, which can cause abdominal pain.