Seahawks vs Cardinals Thursday Night Football Predictions | Best NFL Picks Week 4

🏈 If you are looking for NFL Week 4 picks and predictions for the Seahawks vs Cardinals matchup, we have you covered! Our NFL football handicapping experts discuss the opening weekend from a sports betting perspective, sharing their picks and predictions vs. the current odds. #nflpicks #nflpredictions #thursdaynightfootball Seattle Seahawks @ Arizona Cardinals – NFL Week 4 📅 Date: Thursday, September 25, 2025 🕘 Time: 8:15 PM Eastern Time 📍 Location: State Farm Stadium, Glendale, Arizona How to Watch / Listen / Stream: TV Broadcast: Prime Video will carry the game nationally. Online Streaming: Available via Amazon Prime Video. Radio: Local radio affiliates of each team; Seattle Seahawks Radio Network and Arizona Cardinals Radio Network. (Check local listings for exact station in your area.) Team Hashtags: Seattle Seahawks: #Seahawks Arizona Cardinals: #Cardinals Current Spread / Total: Spread: Cardinals −2.5 vs Seahawks +2.5 Over/Under (Total Points): 46.5 points Interesting Facts & Storylines: The Cardinals enter the game at 2–1 on the 2025 season, under head coach Jonathan Gannon. Arizona is seeking its first NFC West title in several years and is off to its best start (2–0) to begin a season since 2021. Seattle comes in with a 1–1 record. The rivalry between Seattle and Arizona is fairly competitive. All-time series favors the Seahawks, who currently lead 29–22–1. Arizona’s rookie draft pick Walter Nolen (DT) remains unavailable, placed on the Physically Unable to Perform (PUP) list and expected to miss at least the first four games of the season. #SeattleSeahawks vs #ArizonaCardinals 👍 Make sure to SUBSCRIBE to WagerTalk TV; 🔔 CLICK the Bell and never miss an episode! 🏈 More Free NFL Picks: https://www.wagertalk.com/free-sports... 🤑 Free Sports Picks: https://www.wagertalk.com/free-sports... 📊 Live Odds: https://www.wagertalk.com/odds 🗞️ News: https://www.wagertalk.com/news 👍 Stay connected with WagerTalk 📺 YouTube: https://wt.buzz/tv 👍 Facebook: https://wt.buzz/fb 🐦 Twitter: https://wt.buzz/tw 📸 Instagram: https://wt.buzz/ig 📰 Reddit: https://wt.buzz/rd ❤️ iHeart Radio: https://wt.buzz/iheart 🍎 Apple Podcasts: https://wt.buzz/ap 📌 Pinterest: https://wt.buzz/pin