In this lecture we will understand basic pathophysiology of edema and discuss nuances of Starling principles. We will also initiate discussions on Modified Starling principle. Good reads 1. Guyton & Hall : Textbook of Medical Physiology. Thirteenth edition 2. Burton Rose & Theodore Post : Clinical physiology of acid-base and electrolyte disorders. Fifth edition. 3. West’s : Respiratory physiology. Tenth edition. 4. https://derangedphysiology.com/main/c... References : 1. Microvascular fluid exchange and the revised Starling principle. Cardiovasc Res. 2010 Jul 15;87(2):198-210. 2. The Role of the Lymphatic System in Heart Failure . Itkin et al. JACC VOL. 78, NO. 3, 2021:278–90 . 3. Signaling Mechanisms Regulating Endothelial Permeability DOLLY MEHTA AND ASRAR B. MALIK. Physiol Rev 86: 279–367, 2006. Disclaimer: This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. Unless otherwise specified, these lectures are intended only for adult population and may not apply to pediatric/neonates.